This talk considers general issues in the perceptual and acoustic aspects of dysarthria, a neuromotor speech disorder. A primary feature of neuromotor disability is difficulty transmitting information between the central nervous system and muscles, directly affecting muscular control of movement. Muscular control of speech production is also affected, resulting in deviant speech patterns such as imprecise consonants, distorted vowels, hypernasality, and excessive or monotonic intonation (Darley et al., 1969a; Darley et al., 1969b; Darley et al., 1975). This talk will offer an overview of findings in acoustic studies of dysarthria, addressing issues pertaining to 1) reduced intelligibility, i.e., the perceptual aspect of dysarthria, and 2) the acoustic correlates of perceptual judgments of intelligibility (Kim, Martin, Hasegawa-Johnson & Perlman 2010; Kim, Hasegawa-Johnson & Perlman 2011; Kim & Hasegawa-Johnson 2011). In addition, studies on kinematic factors for the perceptual and acoustic deviances in dysarthria will be briefly discussed (Murdoch & Goozee 2003; Kuruvilla, Murdoch & Goozee 2007; Kim, Rong, Loucks & Hasegawa-Johnson 2010), as well as recent efforts to build Universal Access corpus for the development of assistive technologies such as automatic speech recognition systems (Kim et al., 2008). Lastly, a current project on 'Effects of familiarization on dysarthric speech intelligibility' will be described, particularly on the significance of the research topic, choice of instrumentation, and data collection methods.