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Special CPLC Seminar: "Stochastic thermodynamics: Fluctuations, coarse-graining and molecular motors"

SpeakerBernhard Altaner, Ph.D. student of Juergen Vollmer, Max Planck Institute
Date May 17, 2013
Time 2:00 pm  
Location 3110 ESB
Sponsor Center for the Physics of Living Cells
Contact Stephanie Johansson
Phone 217-300-4241
Event type Other
Views 2162

In the last decade or so, statistical mechanics has been applied to biological engines on a mesoscopic scale, rather than its historical focus on the entropy production, dissipation and efficiency of (macroscopic) steam engines,  On this scale of description, fluctuations are not only present but often, through evolution, play a functional role in living systems. Stochastic Thermodynamics (ST) provides an elegant unification of the so-called stochastic fluctuation relations [1] that have been discovered in the last decade or so. In my talk I will review ST and address the question, of whether and how one can switch between different stochastic models by coarse-graining. Motivated by some insights of ST, I propose an algorithm that allows model reduction while preserving the fluctuation spectrum of stochastic dynamics [2]. I will exemplify its efficiency using a stochastic model for the molecular motor protein kinesin. [3]

[1] Seifert, U., Rep. Prog. Phys., 2012, 75, 126001

[2] Altaner, B. & Vollmer, J., Phys. Rev. Lett., 2012, 108, 228101

[3] Liepelt, S. & Lipowsky, R., Phys. Rev. Lett., 2007, 98, 258102

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