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Special CPLC Seminar: "Stochastic thermodynamics: Fluctuations, coarse-graining and molecular motors"

Event Type
Center for the Physics of Living Cells
3110 ESB
May 17, 2013   2:00 pm  
Bernhard Altaner, Ph.D. student of Juergen Vollmer, Max Planck Institute
Originating Calendar
Physics - Physics of Living Cells Seminar

In the last decade or so, statistical mechanics has been applied to biological engines on a mesoscopic scale, rather than its historical focus on the entropy production, dissipation and efficiency of (macroscopic) steam engines,  On this scale of description, fluctuations are not only present but often, through evolution, play a functional role in living systems. Stochastic Thermodynamics (ST) provides an elegant unification of the so-called stochastic fluctuation relations [1] that have been discovered in the last decade or so. In my talk I will review ST and address the question, of whether and how one can switch between different stochastic models by coarse-graining. Motivated by some insights of ST, I propose an algorithm that allows model reduction while preserving the fluctuation spectrum of stochastic dynamics [2]. I will exemplify its efficiency using a stochastic model for the molecular motor protein kinesin. [3]

[1] Seifert, U., Rep. Prog. Phys., 2012, 75, 126001

[2] Altaner, B. & Vollmer, J., Phys. Rev. Lett., 2012, 108, 228101

[3] Liepelt, S. & Lipowsky, R., Phys. Rev. Lett., 2007, 98, 258102

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