Magnetic resonance imaging (MRI) has had a profound impact on biology and medicine. Key to its success has been the unique ability to combine imaging with nuclear magnetic resonance spectroscopy, which has led to a host of powerful modalities for imaging. Although it remains a significant challenge, there is considerable interest in extending these powerful spectroscopic and imaging capabilities to the nanometer scale. In this talk, I will discuss the fundamental physics behind MRI and how we might extend these powerful ideas to image the smallest constituents in biology, such as single virus particles or even single molecules.
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