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Biochemistry Seminar: Dr. Joseph M. Jez (Washington University) "GH3 Proteins as Molecular On/Off Switches of Plant Hormone Action"

Event Type
Seminar/Symposium
Sponsor
Dr. Satish Nair
Location
B102 CLSL
Date
Jan 25, 2013   12:00 - 1:00 pm  
Speaker
Dr. Joesph M. Jez
Cost
Free
Contact
Cara L. Day
E-Mail
caraday@illinois.edu
Phone
217.333.2013
Views
1529
Originating Calendar
Biochemistry Department Seminars

Acyl acid amido synthetases of the GH3 family act as critical pre-receptor modulators of plant hormone action; however, the molecular basis for their hormone selectivity is unclear.  Recent crystal structures of GH3 proteins (Westfall et al., 2012 Science 336, 1708) combined with biochemical analysis define how a highly adaptable three-dimensional scaffold is used for the evolution of promiscuous activity across an enzyme family for modulation of plant signaling molecules.

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