New compounds that specifically attack fungal infections without attacking human cells could transform treatment for such infections and point the way to targeted medicines that evade antibiotic resistance.
Searching a whole genome for one particular sequence is like trying to fish a specific piece from the box of a billion-piece puzzle. Using advanced imaging techniques, University of Illinois researchers have observed how one set of genome-editing proteins finds its specific targets, which could help them design better gene therapies to treat disease.
Dolphins found stranded on Gulf of Mexico beaches following the 2010 Deepwater Horizon oil spill were much more likely to have severe lung and adrenal gland damage “consistent with petroleum product exposure” than dolphins stranded elsewhere and prior to the spill, researchers report. One in five dolphins from the spill zone also had primary bacterial pneumonia.
A study of older adults at risk of late-onset Alzheimer’s disease found that those who consumed more omega-3 fatty acids did better than their peers on tests of cognitive flexibility – the ability to efficiently switch between tasks – and had a bigger anterior cingulate cortex, a brain region known to contribute to cognitive flexibility.
A new study offers insights into the genetic changes that accompany social complexity in bees, including honey bees. Carl R. Woese Institute for Genomic Biology faculty members Saurabh Sinha, a professor of computer science; Gene Robinson, a professor of entomology and IGB director; and an international consortium of 52 scientists used comparative genomics to discover that the evolution of bee society is associated with increases in the complexity of gene regulation.
Some species of trap-jaw ants use their spring-loaded mandibles to hurl themselves out of harm’s way when an ant-trapping predator stalks, researchers report in the journal PLOS ONE. This dramatic maneuver doubles the ants’ survival when other escape methods fail, the researchers found.