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  • Development and/or Validation of Devices or Electronic Systems to Monitor or Enhance Mind and Body Interventions (R41/R42)

    This FOA from the National Center for Complementary and Integrative Health (NCCIH) supports Small Business Technology Transfer (STTR) grant applications from small business concerns (SBCs) that will develop and/or validate devices or electronic systems that can: 1) monitor biologically- or behaviorally-based processes applicable to mind and body interventions or 2) be used to assist in optimizing the practice or increasing the efficacy of mind and body interventions.  The applications should: 1) lead to the development of new technologies, 2) adapt existing innovative technologies, devices and/or electronic systems, 3) repurpose existing devices and electronic systems, or 4) conduct testing of single or combined components of an integrated, long term, automated, wearable monitoring, stimulation device or electronic system in order to monitor or enhance the mechanistic processes or functional outcomes of mind and body interventions. For the purposes of this FOA, mind and body interventions are defined as non-pharmacological approaches that include mind/brain focused interventions (e.g., meditation, hypnosis), body-based approaches (e.g., acupuncture, massage, spinal manipulation/mobilization), or combined mind and body meditative movement approaches (e.g., yoga, tai-chi, qigong). Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity.

    Amount: According to statutory guidelines, total funding support (direct costs, indirect costs, fee) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% as a hard cap ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH has received a waiver from SBA, as authorized by statute, to exceed the hard cap of $225,000 for Phase I or $1,500,000 for Phase II for specific topics. 

    Deadline(s): 1/5/2018, 4/5/2018, 9/5/2018, 1/5/2019, 4/5/2019, 9/5/2019, 1/5/2020

    RFP

  • Stanley Fahn Junior Faculty Award - Parkinson's Disease

    The award, from the Parkinson's Disease Foundation (PDF), acts as a bridge to ensure that promising early career scientists stay in the field of Parkinson’s research and help us solve, treat and end the disease. The impetus behind the award is to stem the loss of talent from Parkinson’s research. The award provides junior investigators — in conjunction with their institution’s commitment — with the support necessary to develop their own independent funding source (such as an NIH R01 award) and stay in the field of PD research. The ultimate goal is for the investigator to become an independent research leader with his or her own research space.

    Junior faculty members possessing a Ph.D., M.D. or equivalent are eligible to apply. Applicants must generally meet the NIH definition of a "new investigator." PDF anticipates the typical applicant will hold an assistant professor level position with up to several years of experience. Earlier stage faculty and those with more experience will be considered provided that the above eligibility criteria are met. The award is open to applicants, regardless of citizenship, who reside in the US and are faculty members of US institutions. 

    Amount: $300,000 in total costs. Indirect costs, not exceeding 10 percent of direct costs, may be deducted from the total. Applicant salary support is permitted up to 40 percent of total salary

    Letter of Intent Deadline: 11/27/17

    Application submissions accepted by invitiation only.

    RFP

  • Fundamental Science Research on Mind and Body Approaches (R01, R21)

    The National Center for Complementary and Integrative Health (NCCIH) seeks applications for the following awards:

    - Fundamental Science Research on Mind and Body Approaches (R01) RFP

    - Fundamental Science Research on Mind and Body Approaches (R21) RFP

    For more information about these awards, please click here.

  • Developing Interventions for Health-Enhancing Physical Activity (R21/R33)

    The purpose of this FOA is to fund highly innovative and promising research aimed at developing multi-level physical activity intervention programs acting on at least two levels of the socioecological model and designed to increase health-enhancing physical activity: 1) in persons or groups that can benefit from such activity; and 2) that could be made scalable and sustainable for broad use across the nation. This FOA provides support for up to two years (R21 phase) for research planning activities and feasibility studies, followed by a possible transition to expanded research support (R33 phase - clinical trial optional) for optimizing the intervention and conducting larger-scale feasibility studies. Transition to the R33 depends on the completion of applicant-defined milestones, as well as program priorities and the availability of funds.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.

    Amount: The R21 phase may not exceed $275,000 in direct costs for the 2-year project period, with no more than $200,000 in direct costs in any single year of the R21 phase. The R33 phase may not exceed $750,000 in direct costs for the 3-year project period, with no more than $250,000 in direct costs in any single year of the R33 phase.

    Deadline(s): 2/16/18; 10/16/18; 6/16/19; 2/16/20; 10/16/20

    RFP

  • Testing Interventions for Health-Enhancing Physical Activity (R01)

    The purpose of this FOA is to fund highly innovative and promising research that tests multi-level physical activity intervention programs acting on at least two levels of the socio-ecological model and designed to increase health-enhancing physical activity: 1) in persons or groups that can benefit from such activity; and 2) that could be made scalable and sustainable for broad use across the nation.  This FOA provides support for up to 5 years for research planning, intervention delivery, and follow-up activities. Clinical trials are optional.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): 2/5/18; 10/5/18; 6/5/19; 2/5/20; 10/5/20

    RFP

  • AD Biomarker-Based Clinical Trials in Humans

    The goal of this RFP, "AD Biomarker-Based Clinical Trials in Humans - Innovative Approaches to Science and Engineering Research on Brain Function," is to increase the number of innovative treatments tested in humans for Alzheimer's disease, related dementias, and cognitive aging. This program will fund exploratory Phase 0 microdosing studies that assess preliminary target engagement and PK, Phase I safety testing, Phase 2 biomarker-based proof-of-concept clinical trials in patients, as well as IND-enabling studies to accelerate new drugs into trials. Through this PACT RFP, the Alzheimer's Drug Discovery Foundation (ADDF) is also interested in supporting biomarker-based trials to validate putative mechanisms of action for targeted pharmacological and non-pharmacological approaches to prevention.

    Amount: Grants of up to $3 million will be awarded for biomarker-based pilot clinical trials

    Letter of Intent Deadline: November 17, 2017

    Applications submissions accepted by invitation only.

    RFP

  • Collaborative Research in Computational Neuroscience (CRCNS)

    The CRCNS program supports collaborative activities that will advance the understanding of nervous system structure and function, mechanisms underlying nervous system disorders, and computational strategies used by the nervous system. Two classes of proposals will be considered in response to this solicitation: Research Proposals describing collaborative research projects, and Data Sharing Proposals to enable sharing of data and other resources.

    Deadline(s): 1/5/2018, 11/27/2018, 11/25/2019

    RFP

    For more information about this award, please click here.

  • Opportunities for Collaborative Research at the NIH Clinical Center (X02, U01)

    The NIH seeks applications for the following awards:

    - Pre-application: Opportunities for Collaborative Research at the NIH Clinical Center (X02) RFP

    Deadline: 12/15/17

    - Opportunities for Collaborative Research at the NIH Clinical Center (U01) RFP

    Deadline: 4/11/18

    For more information about these awards, please click here.

  • Autism Pilot and Research Awards

    The mission of the Simons Foundation Autism Research Initiative (SFARI) is to improve the diagnosis and treatment of autism spectrum disorders by funding, catalyzing, and driving research of the highest quality. The program is seeking applications for SFARI awards from individuals who will conduct bold, imaginative, rigorous, and relevant research. Applications are invited in two categories: SFARI Pilot Awards and SFARI Research Awards.

    All applicants and key collaborators must hold a Ph.D., M.D., or equivalent degree and have a faculty position or equivalent at a college, university, medical school, or other research facility. Applications may be submitted by domestic and foreign nonprofit organizations; public and private institutions such as colleges, universities, hospitals, laboratories, units of state, and local government; and eligible agencies of the federal government. There are no citizenship or country requirements.

    Amount: Max. for pilot award is $330,000; Max. for research award is $975,000

    Letter of Intent Deadline (for both awards): 12/1/17

    Application Deadline (for both awards): 2/26/18

    RFP

  • Parkinson's Disease Mentored Clinical Research Award

    The Mentored Clinical Research Award (MCRA) for new investigators is funded by a grant from the Parkinson’s Foundation (PF) to the Parkinson Study Group (PSG). The purpose of this grant is to support a new investigator for a 1-year project in patient oriented research in Parkinson's disease or other parkinsonian disorders under the mentorship of an experienced investigator. The goal of the Award is to provide funding for an investigator with the potential to become an independent researcher. Appropriate applicants for the MCRA are clinicians and scientists who are within 5 years of having completed formal training. The applicant must identify an appropriate mentor or mentors with extensive research experience. Further, either the applicant or the mentor must be a member of the PSG.

    Amount: $50,000

    Deadline: 1/12/2018

    RFP

  • McKnight Foundation Awards

    The McKnight Endowment Fund for Neuroscience, as part of The McKnight Foundation, seeks applications for the following awards:

    - McKnight 2018 Scholar Awards RFP

    - McKnight 2018 Technology Awards RFP

    For more information about these awards, please click here.

  • NIH SIREN Neurologic Clinical Trials (U01)

    This FOA encourages applications for multi-center clinical trials focused on neurological emergencies.  Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols. The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies. Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): 2/5/2018, 6/5/2018, 10/5/2018, 2/5/2019, 6/5/2019, 10/5/2019, 2/5/2020, 6/5/2020, 10/5/2020

    RFP

  • DoD Medical Simulation and Information Sciences Research Program (MSISRP) Award

    The Department of Defense (DoD) seeks applications for the FY17 Toward A Next-Generation Trauma Care Capability: Foundational Research for Autonomous, Unmanned, and Robotics Development of Medical Technologies (FORwARD) Award, available through the Medical Simulation and Information Sciences Research Program (MSISRP).

    Amount: The anticipated total costs budgeted for the entire 2 year period of performance will not exceed $1,300,000 per award

    Pre-Application Deadline: November 20, 2017

    Application Deadline: February 5, 2018

    RFP

  • Continuation of the AMP-AD Target Discovery and Preclinical Validation Consortium (U01)

    The goal of this FOA (clinical trial optional) is to continue and expand the open-science, systems-biology enterprise of the AMP-AD Target Discovery and Preclinical Validation Consortium and enable data-driven discovery and validation of novel targets and biomarkers for AD and AD-related dementias through the development of predictive network models of brain health and disease.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Annual direct costs are capped at $1,000,000

    Letter of Intent Deadline: January 20, 2018

    Application Deadline: February 20, 2018

    RFP

  • NIH Blueprint D-SPAN Award (F99/K00)

    The purpose of the NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award is to support a defined pathway across career stages for outstanding graduate students who are from backgrounds that are nationally underrepresented in neuroscience research. This two-phase award will facilitate completion of the doctoral dissertation and transition of talented graduate students to strong neuroscience research postdoctoral positions, and will provide career development opportunities relevant to their long-term career goal of becoming independent neuroscience researchers.

    By the time of award, the individual must be a citizen or a non-citizen national of the United States or have been lawfully admitted for permanent residence (i.e., possess a currently valid Permanent Resident Card USCIS Form I-551, or other legal verification of such status).

    Amount: For the F99 phase, award budgets are composed of stipends, tuition and fees, and institutional allowance. For the K00 phase, award budgets are composed of salaries and fringe benefits, research and career development support, and indirect costs.

    Letter of Intent Deadline: 30 days prior to application deadline

    Application Deadline: December 13, 2017

    RFP

  • Edward M. Scolnick Prize in Neuroscience

    The Edward M. Scolnick Prize Neuroscience is awarded annually by the McGovern Institute for Brain Research at MIT to recognize outstanding advances in the field of neuroscience. The prize, which is endowed through a gift from Merck to the McGovern Institute, consists of a $150,000 award, plus an inscribed gift. The recipient of the Scolnick Prize presents a public lecture at the McGovern Institute for Brain Research in the spring of 2018. A dinner for the recipient and invited guests follows the prize lecture.

    Candidates for the award must be nominated by individuals affiliated with universities, hospitals, medicals schools, or research institutes, with a background in neuroscience. Self-nomination is not permitted.

    Amount: $150,000

    Deadline: December 15, 2017

    RFP

  • NINDS Ruth L. Kirschstein National Research Service Award (NRSA) (F32)

    The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows is to support outstanding scientific training of highly promising postdoctoral candidates with outstanding mentors. Candidates are eligible to apply for support from this program from ~12 months prior to the start of the proposed postdoctoral position to within 12 months after starting in postdoctoral position. Based on the early timeframe of eligibility, and the discouragement of inclusion of preliminary data, this NINDS F32 seeks to foster early, goal-directed planning and to encourage applications for bold and/or innovative projects by the candidate that have the potential for significant impact.

    Applications are expected to incorporate strong training in quantitative reasoning and the quantitative principles of experimental design and analysis. Support by this program is limited to the first 3 years of a candidate's activity in a specific laboratory or research environment, so as to further encourage early fellowship application and timely completion of “mentored training” of the postdoctoral candidate in a single environment.

    Amount: Award budgets are composed of stipends, tuition and fees, and institutional allowance

    Deadline(s): 12/8/2017, 4/8/2018, 8/8/2018, 12/8/2018, 4/8/2019, 8/8/2019

    RFP

    For additional eligibility information, please click here.

  • Alzheimer's Drug Discovery Program Awards

    The Alzheimer's Drug Discovery Foundation (ADDF) seeks applications for the following awards:

    - Biomarkers Development RFP

    - Prevention Beyond the Pipeline RFP

    For more information about these awards, please click here.

  • Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R01, R21)

    The National Institute on Aging (NIA) seeks applications for the following awards:

    - Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R01) RFP

    - Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R21) RFP

    For more information about these awards, please click here.

  • BRAIN Initiative Awards (R01s, R21, U01s, UG3/UH3)

    The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative seeks applications for the following awards:

    R01s

    - Tools to target, identify and characterize non-neuronal cells in the brain RFP

    - Tools to Facilitate High-Throughput Microconnectivity Analysis RFP

    - Research on the Ethical Implications of Advancements in Neurotechnology and Brain Science RFP

    - Targeted BRAIN Circuits Projects (TargetedBCP) RFP

    - Proof of Concept Development of Early Stage Next Generation Human Brain Imaging RFP

    - Theories, Models and Methods for Analysis of Complex Data from the Brain RFP

    R21

    - New Concepts and Early - Stage Research for Large - Scale Recording and Modulation in the Nervous System RFP

    UG3/UH3

    - Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System RFP

    U01s

    - Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP RFP

    - Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain RFP

    - Development of Next Generation Human Brain Imaging Tools and Technologies RFP

    For more information about these awards, please click here. The earliest deadline is October 18, 2017. 

  • Novel Approaches to Diagnosing Alzheimer's Disease & Predicting Progression (R01)

    This FOA encourages research applications to identify novel biomarkers to diagnose Alzheimer’s disease and to predict clinical course. These novel biomarkers should provide new biological information about patients with dementia and/or address the shortcomings of currently-validated biomarkers.

    This FOA hopes to facilitate projects that will accomplish one or more of 3 aims: identifying new biomarkers that provide novel insights into the pathophysiological basis of AD; identifying new biomarkers that are minimally invasive, inexpensive, usable in community settings, and that could be used for screening a general population; and/or identifying new biomarkers that could serve as surrogate measures for disease progression in AD.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): February 5, 2018 and June 5, 2018

    RFP

  • Phase III Clinical Trials for the Spectrum of Alzheimer's Disease and Age-related Cognitive Decline (R01)

    This FOA encourages R01 grant applications that propose to develop and implement Phase III clinical trials of promising pharmacological and non-pharmacological interventions in individuals with age-related cognitive decline and across the Alzheimer's disease (AD) spectrum from pre-symptomatic to more severe stages of disease.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Letter of Intent Deadline: 30 days prior to application deadline

    Application Deadline(s): February 5, 2018 and June 5, 2018

    RFP

  • Biobehavioral and Technological Interventions to Attenuate Cognitive Decline in Individuals with Cognitive Impairment or Dementia (R21)

    The purpose of this FOA is to stimulate clinical research focused on biobehavioral or technological interventions to attenuate cognitive decline in individuals with dementia (such as Alzheimer’s disease, Lewy body dementia, vascular dementia), mild cognitive impairment (MCI), or disease- or age-related cognitive decline. There is particular interest in interventions that can be implemented in community settings by the affected individual, informal caregivers, or others in the community. Research to inform the development of such interventions is also of interest, as well as research examining underlying mechanisms and biomarkers associated with response to interventions. It is anticipated that the results of this research will help affected individuals maintain independence and quality of life, improve their ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), and additionally help to reduce stress, burden, and other poor outcomes in their caregivers.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: The combined budget for direct costs for the two year project period may not exceed $275,000. No more than $200,000 in direct costs may be requested in any single year

    Deadline: October 16, 2017

    RFP

  • Research on Autism Spectrum Disorders (R01)

    The purpose of this FOA is to encourage research grant applications to support research designed to elucidate the etiology, epidemiology, diagnosis, treatment, and optimal means of service delivery in relation to Autism Spectrum Disorders (ASD).

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): 2/5/2018, 6/5/2018, 10/5/2018, 2/5/2019, 6/5/2019

    RFP

  • Capturing Complexity in the Molecular and Cellular Mechanisms Involved in the Etiology of Alzheimer's Disease (R01)

    The goal of this FOA is to support innovative research focused on understanding the molecular and cellular mechanisms underlying the heterogeneity and multifactorial nature of Alzheimer’s disease (AD) with the potential to create new or challenge existing scientific paradigms. This FOA encourages individual or collaborative research projects that propose innovative approaches to understand the complex biology of AD aimed to fill critical knowledge gaps.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): Februrary 5, 2018 and June 5, 2018

    RFP

  • Understanding Alzheimer's Disease in the Context of the Aging Brain (R01)

    The goal of this FOA is to establish the role and impact of brain aging in the development and progression of Alzheimer’s disease (AD). Comprehensive and integrative characterization of brain aging will help to define the mechanisms underlying the shift from healthy brain aging to the neuropathological processes of AD, knowledge that is critical for the design and development of effective interventions. Cross-disciplinary approaches to integrate findings on AD with research on the basic biology and neurobiology of aging are encouraged. 

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadlines: February 5, 2018 and June 5, 2018

    RFP

  • Pilot Clinical Trials for the Spectrum of Alzheimer’s Disease and Age-related Cognitive Decline (R01)

    This FOA invites applications that propose to develop and implement Phase I or II clinical trials of promising pharmacological and non-pharmacological interventions in individuals with age-related cognitive decline and in individuals with Alzheimer's disease (AD) across the spectrum from pre-symptomatic to more severe stages of disease, as well as to stimulate studies to enhance trial design and methods.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): 10/5/2017, 2/5/2018, 6/5/2018

    RFP

  • Engineering Next-Generation Human Nervous System Microphysiological Systems (R21)

    This FOA encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) with improved fidelity to complex human brain, spinal, peripheral nervous system and/or sensory end organ circuit physiology in vivo, which will ultimately facilitate analysis of higher order functional deficits relevant to complex nervous system disorders.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year

    Deadline(s): 10/16/2017, 2/16/2018, 6/16/2018, 10/16/2018, 2/16/2019, 6/16/2019, 10/16/2019

    RFP

  • Major Opportunities for Research in Epidemiology of Alzheimer's Disease and Cognitive Resilience (R01)

    This FOA encourages investigator-initiated applications addressing the epidemiology of Alzheimer’s disease (AD) as well as protective factors for cognitive health and resilience. All projects in cognitive epidemiology and genetics/genomics relevant to AD are welcome. NIA especially encourages projects or revisions to projects that propose: augmenting existing longitudinal cohort studies; enabling precision medicine for AD; enhancing the power of multi-ethnic cohort studies; exploring trends in the risk of AD and their explanation via putative risk and protective factors; collecting and sequencing DNA samples from well-characterized cases and controls; electronic archiving of cohort studies; harmonizing complex data sets relevant to AD; and harmonizing dementia assessment to enhance cross-national comparisons.

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): February 5, 2018 and June 5, 2018

    RFP

  • American Psychological Foundation - Early Career Grant

    The American Psychological Foundation (APF) seeks applications for the David Wechsler Early Career Grant for Innovative Work in Cognition. Through the annual program, one grant of up to $25,000 will be awarded to support an early-career psychologist pursuing innovative work in neuropsychology, intelligence, and/or the assessment aspects of cognition. Those who work on positive applied neuropsychology are encouraged to apply.

    To be eligible, psychologists must hold an Ed.D., Psy.D., or Ph.D. from an accredited university and be no more than seven years postdoctoral.

    Amount: $25,000

    Deadline: June 15, 2018

    RFP

  • Research on Informal and Formal Caregiving for Alzheimer's Disease (R01, R21)

    The National Institute on Aging (NIA) and National Institute of Nursing Research (NINR) seek applications for basic and translational research on caregiving for individuals with Alzheimer’s disease (AD), at the individual, family, community, and population level:

    - Research on Informal and Formal Caregiving for Alzheimer's Disease (R01) RFP

    - Research on Informal and Formal Caregiving for Alzheimer's Disease (R21) RFP

    For more information about these awards, please click here.

  • NINDS Morris K. Udall Centers of Excellence for Parkinson's Disease Research (P50)

    This FOA invites applications for the Morris K. Udall Centers of Excellence for Parkinson’s Disease Research program. The overarching goal of the specialized Udall Centers program is to establish a network of Centers that work collaboratively as well as independently to define the causes of and discover improved treatments for Parkinson’s disease (PD). A more immediate goal for each Center is to rapidly advance synergistic, interdisciplinary research programs while serving as national leaders in PD research. Udall Centers also serve as local resources by organizing research career enhancement activities for Center investigators and periodic outreach to the PD patient/advocacy community.

    Amount: Applicants may request up to $1,000,000 direct costs per year with the follow exception: applications containing a translational project and/or clinical component (i.e. clinical research project plus a clinical core) may request up to $1,500,000 direct costs per year

    Letter of Intent Deadline: November 15, 2017

    Application Deadline: December 15, 2017

    RFP

    For more information about this opportunity, please click here.

  • Development of Valid Reliable Markers of Aging-Related Biologic Mechanisms for Human Studies (U01)

    This FOA, from the National Institute on Aging (NIA), encourages applications to develop valid markers to assess the activity of fundamental aging mechanisms in humans that may influence the risk and progression of multiple aging conditions. Projects are encouraged that focus on selected mechanism(s) that may regulate aging changes, assess multiple possible markers for these mechanisms, test methods to improve their measurement properties, characterize their variability among individuals of differing ages and within the same age cohort, and assess their relationships in humans to in vivo functions influenced by the mechanism(s) under study.

    Please note: Clinical trial application submissions are not permitted for this award.

    Amount: A budget of up to $400,000 per year in direct costs may be requested. Application budgets need to reflect the actual needs of the proposed project

    Letter of Intent Deadline: December 30, 2017

    Application Deadline: January 30, 2018

    RFP

    For more information about this funding opportunity, please click here.

  • Additional Sequencing for the Alzheimer's Disease Sequencing Project (U01)

    This Limited Competition FOA invites applications specific to sample acquisition, genome wide association studies, whole genome sequencing, quality control checking, variant calling, and data calling that will support the generation of data for the Alzheimer's Disease Sequencing Project Follow-Up Study. 

    Only PD/PIs, key personnel, and collaborators supported under PA 12-183, PAR 14-070, and PAR 16-001 may be PDs/PIs of applications for this Limited Competition FOA and they must have access to a sequencing center either through a subcontract or as part of the application.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Letter of Intent Deadline: 30 days prior to the application deadline (Limited Competition)

    Application Deadline(s): 2/5/2018, 6/5/2018, 10/5/2018, 2/5/2019, 6/5/2019

    RFP

  • High Impact Neuroscience Research Resource Grants (R24)

    This FOA, from the National Institute of Neurological Disorders and Stroke (NINDS), supports high impact efforts to make resources available to neuroscience researchers. Projects should engage in one or more of the following activities: facilitating access to cutting edge reagents or techniques, dissemination of resources to new user groups, or innovative approaches to increase the scale/efficiency of resource production and delivery.

    Applications focused primarily on technology or software development are not responsive to this FOA, as the focus is on dissemination or provision of resources. Use of existing technologies to develop new reagents or genetic lines of significant value to the research community may be appropriate. Projects should address compelling needs of broad communities of neuroscience researchers or should offer unique services that otherwise would be unavailable. Projects must support the NINDS mission. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Please note: Clinical trial application submissions are not permitted for this award.

    Amount: The combined budget for direct costs for the entire project period may not exceed $700,000. No more than $350,000 may be requested in any single year.

    Letter of Intent Deadline: 30 days prior to the application deadline

    Application Deadline: February 9, 2018

    RFP

  • Epilepsy Foundation Invites Entries for 2018 Shark Tank Competition

    The Epilepsy Foundation has announced its seventh annual epilepsy “Shark Tank” competition for the most innovative ideas in epilepsy and seizure treatment and care. Some examples of novel ideas include a system to detect seizures and provide early warning to the patient or family; a treatment that stops a seizure from progressing; a system that helps patients manage their daily treatment; a device that prevents physical injury that patients may experience when in seizure; or an entirely new product concept with the potential to dramatically improve the lives of people with epilepsy.

    Applicants must demonstrate an ability to move the proposed plan to completion, showing how the prize can accelerate any step along the path to market. Inventors who submitted ideas for previous Shark Tank Competitions are encouraged to re-submit their ideas if substantial progress has been made. Applicants may reside in any country. No specific background or experience is required.

    Amount: $150,000

    Letter of Intent Deadline: October 16, 2017

    Applications accepted by invitation only.

    RFP

  • CART Alzheimer's Research Awards

    Rotary International (RT) seeks applications for the Coins for Alzheimer's Research Trust (CART) Awards. The goal of the CART fund is to encourage exploratory and developmental AD research projects within the United States. This is accomplished by providing financial support for the early and conceptual plans of those projects that may not yet be supported by extensive preliminary data but have the potential to substantially advance biomedical research.

    Eligible applications may come from full time faculty (or equivalent status) at U.S. based public and private institutions, such as universities, colleges, hospitals, and laboratories.

    Amount: $250,000

    Letter of Intent Deadline: December 1, 2017

    Applications accepted by invitation only.

    RFP

  • NINDS Renewal Awards of SBIR Phase II Grants (R44)

    The National Institute of Neurological Disorders and Stroke (NINDS) seeks applications for the following Renewal Awards:

    - SBIR Phase IIB Clinical Trials and Clinical Research (R44) RFP

    Letter of Intent Deadline: 30 days prior to the application deadline

    Application Deadline: 1/5/2018

    - SBIR Phase IIB Pre-Clinical Research (R44) RFP

    Letter of Intent Deadline: 30 days prior to the application deadline

    Application Deadline(s): 1/5/2018, 4/5/2018, 9/5/2018, 1/5/2019, 4/5/2019, 9/5/2019, 1/5/2020, 4/5/2020, 9/5/2020

    For more information about these opportunities, please click here.

  • DoD Psychological Health/Traumatic Brain Injury Research Program Awards

    The Department of Defense (DoD) Psychological Health/Traumatic Brain Injury Research Program seeks applications for the following awards:

    - Complex Traumatic Brain Injury Rehabilitation Research Clinical Research Award RFP

    - Complex Traumatic Brain Injury Rehabilitation Research Clinical Trial Award RFP

    Letter of Intent Deadline (for both awards): October 11, 2017

    Full applications accepted by invitiation only.

    For more information about these opportunities, please click here.

  • PET and SPECT Imaging Ligands as Biomarkers of CNS Disorders (R01)

    This FOA, "Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01)," invites research grant applications from organizations/institutions that propose the development of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) imaging in human brain, and that incorporate pilot or clinical feasibility evaluation in pre-clinical studies, model development, or clinical studies. 

    Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): 10/5/2017, 2/5/2018, 6/5/2018, 10/5/2018, 2/5/2019, 6/5/2019

    RFP

  • Centers Without Walls for Collaborative Research in the Epilepsies: Functional Evaluation of Human Genetic Variants (U54)

    The goal of this Epilepsy Center without Walls (CWOW) is to improve understanding of the functional consequences of genetic variants and accelerate progress in translating genomics to allow biologically based diagnoses, individualized treatments and target identification for the development of novel therapeutic agents. The CWOW award will support studies of the functional, pharmacological, neuronal network activity and whole animal consequences of causal and putatively causal genetic variants, generation of key resources (e.g., animal models, induced Pluripotent Stem Cells (iPSCs) for assessment of these variants, and development of strategies to classify variants as treatment targets and establish diagnostic criteria. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are limited to $1,500,000 direct costs per year

    Letter of Intent Deadline: October 15, 2017

    Application Deadline: January 16, 2018

    RFP

  • Building Trust and Mutual Respect to Improve Health Care

    The Robert Wood Johnson Foundation (RWJF) 2017 Building Trust and Mutual Respect to Improve Health Care award will fund empirical research studies to help better understand how to build trust and mutual respect to meet vulnerable patients’ health care needs. Vulnerable populations include the economically disadvantaged, diverse racial and ethnic populations, the uninsured, older adults, homeless individuals, and people with complex health and social needs (including people with acute behavioral health needs or multiple chronic conditions). Proposals most closely aligned with the scope of this RFP will go beyond documenting the problem to generate findings that will be generalizable and have broad application across health systems and the field.

    Amount: Recommended project funding is up to $250,000 to accommodate studies of 18–24 months. Projects that exceed the recommended budget range must provide strong justification for the proposed budget. Up to $1,100,000 will be available to fund three to five studies.

    Brief Proposal Deadline: October 13, 2017

    Full proposals accepted by invitation only.

    RFP

  • Grants for Alzheimer's and Glaucoma Research

    The BrightFocus Foundation provides research funds for high-risk studies that illuminate areas for which there currently is little understanding, helping to bring to light crucial knowledge about Alzheimer’s disease, glaucoma, and macular degeneration. To that end, the foundation is accepting applications for its Alzheimer's Disease Research and National Glaucoma Research programs.

    Grants will be awarded to researchers for innovate investigator-initiated research projects. These programs are designed to give scientists the opportunity to develop the preliminary data necessary to be considered competitive for larger government or corporate types of sponsorship. Note: Typically these awards are made to junior investigators, or to more established investigators who are proposing particularly innovative research.

    - Alzheimer's Disease Research Program

    Amount: Up to $300,000 over three years

    Deadline: October 18, 2017

    - National Glaucoma Research Program

    Amount: Up to $150,000 over two years

    Deadline: November 7, 2017

    RFP

  • Greenwall Foundation Faculty Scholars Program in Bioethics

    The Greenwall Foundation Faculty Scholars Program in Bioethics is a career development award that supports innovative bioethics research by junior faculty members. Each year, up to three Greenwall Faculty Scholars are selected. The program supports research that goes beyond current work in bioethics to pressing ethical issues in clinical care, biomedical research, and public policy. 

     

    This is a limited submission opportunity. Up to two applicatns from a university will be considered in each application cycle. The OVCR will manage the campus limited selection process. The preproposal form can be found here.

     

    Amount: 50 percent of a scholar's salary plus benefits for three years, with 10 percent institutional costs for the salary and benefits. In addition, the program provides $5,000 per year for limited project support and travel (no indirect costs).

     

    Preproposal materials deadline: October 12, 2017

     

    RFP

     

    For more information about this opportunity, please click here.

  • BRAIN Initiative: Tools to Facilitate High-Throughput Microconnectivity Analysis (R01)

    The purpose of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate tools and resources to facilitate the detailed analysis of brain microconnectivity. Novel and augmented techniques are sought that will ultimately be broadly accessible to the neuroscience community for the interrogation of microconnectivity in healthy and diseased brains of model organisms and humans. Development of technologies that will significantly drive down the cost of connectomics would enable routine mapping of the microconnectivity on the same individuals that have been analyzed physiologically, or to compare normal and pathological tissues in substantial numbers of multiple individuals to assess variability.

    Advancements in both electron microscopy (EM) and super resolution light microscopic approaches are sought. Applications that propose to develop approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged. Proof-of-principle demonstrations and/or reference datasets enabling future development are welcome, as are improved approaches for automated segmentation and analysis strategies of neuronal structures in EM images. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but must reflect the actual needs of the proposed project

    Letter of Intent Deadline: 30 days prior to the application deadline

    Application Deadline: December 7, 2017 and November 13, 2018

    RFP

  • Understanding and Modifying Temporal Dynamics of Coordinated Neural Activity (R01, R21)

    A rich body of evidence suggests that optimal cognitive, affective, and social processes are associated with highly coordinated neural activity. These findings suggest that oscillatory rhythms, their co-modulation across frequency bands, spike-phase correlations, spike population dynamics, and other patterns might be useful drivers of therapeutic development for treatment of cognitive, social, or affective symptoms in neuropsychiatric disorders. These funding opportunities support projects that test whether modifying electrophysiological patterns during behavior can improve cognitive, affective, or social processing.

    - Understanding and Modifying Temporal Dynamics of Coordinated Neural Activity (R01) RFP

    - Understanding and Modifying Temporal Dynamics of Coordinated Neural Activity (R21) RFP

    For more information about these awards, please click here.

  • Weil Foundation Grants for Integrative Medicine

    The Weil Foundation supports the advancement of Integrative Medicine by making grants for training, research, education of the public, and policy reform. The current strategic focus of the Foundation is the training and education of physicians and other health care professionals in Integrative Medicine. Integrative medicine emphasizes the innate healing capacities of the organism; views patients as mental-emotional beings, spiritual entities, and community members as well as physical bodies; addresses all aspects of lifestyle in evaluating health and illness; places great importance on the role of the practitioner-patient relationship in the healing process; and makes use of all appropriate therapies.

    Grant proposals must explain how the activity for which Weil Foundation support is sought advances the mission and the current strategic focus of the Foundation.

    Amount: Varies; Grants awarded from $10,000 to $300,000

    Deadline: January 31, 2018

    RFP

  • Leukemia & Lymphoma Society Translational Research Program

    The Leukemia & Lymphoma Society (LLS) is the world's largest voluntary health agency dedicated to funding blood cancer research, education, and patient services. Its mission is to cure leukemia, lymphoma, Hodgkin's disease and myeloma, and improve the quality of life of patients and their families. To advance these goals, the society's Translational Research Program was developed to encourage and provide early support for clinical research in leukemia, lymphoma, and myeloma focused on innovative approaches to treatment, diagnosis, and prevention.

    The program is designed to support new and innovative research that demonstrates high promise for translating basic biomedical knowledge to clinical application. Projects should be based on molecular, cellular, or integrated systems findings and be conceptually innovative. To be eligible, applicants must hold an MD, PhD, or equivalent degree and work in a domestic or foreign nonprofit organizations such as a university, college, hospital, or laboratory.

    Amount: Up to $600,000 over three years

    Letter of Intent Deadline: September 29, 2017

    RFP

  • Cystic Fibrosis - Pilot and Feasibility Research Grants

    The mission of the Cystic Fibrosis Foundation is to cure cystic fibrosis and to provide all people with the disease the opportunity to lead full, productive lives by funding research and drug development, promoting individualized treatment, and ensuring access to high-quality, specialized care. To advance this mission, the foundation is accepting applications for its Pilot and Feasibility Awards program. Grants of up to $100,000 over two years will be awarded for the development and testing of new hypotheses and/or new methods in CF prevention or treatment, and to support promising new investigators as they establish themselves in research areas relevant to cystic fibrosis.

     

    Priority will be given to projects that propose to better understand the mechanisms behind disease pathophysiology and to develop strategies to prevent or treat CF. Applicants may submit only one Pilot and Feasibility Award application per calendar year (either the spring or fall cycle). Spring applications are due in April; Fall applications are due in September.

     

    Amount: Up to $100,000 over two years (plus 8% for indirects)

     

    Deadline: September 13, 2017

     

    RFP

  • Common Mechanisms and Interactions Among Neurodegenerative Diseases (R01)

    This FOA encourages preclinical and clinical research to study whether, and how, different neurodegenerative disease processes interact with one another to initiate and/or hasten progression of neuropathology and dementia. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for NIH support.

    Amount: Application budgets are not limited but must reflect the actual needs of the proposed project

    Deadline(s): October 5, 2017 and February 5, 2018

    RFP