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  • Pathogenesis of Infectious Disease (PATH)

    The Burroughs Wellcome Fund seeks pre-proposal applications for the Investigators in Pathogenesis of Infectious Disease (PATH) Award. PATH is a career development award to support accomplished investigators at the assistant professor level to study pathogenesis, with a focus on the interplay between infectious agents and their hosts. The program supports research focused on the fundamentals that affect the outcomes of these interactions: how colonization, infection, commensalism, and other relationships play out at levels ranging from molecular interactions to systemic ones.

    This award is intended to give recipients the freedom and flexibility to pursue new avenues of inquiry and higher-risk research projects that hold potential for significantly advancing understanding of the pathogenesis of infectious disease. Researchers who focus on the human host and those whose focus on infectious agents will both be considered.  The program emphasizes research that opens up unexplored areas. Research on under-studied infectious diseases, including pathogenic fungal, protozoan, and metazoan diseases and emerging infections is especially of interest. In addition, excellent animal models of human disease, including in veterinary research settings, are within the program’s scope. Interdisciplinary approaches are encouraged. Work that additionally involves more elements, for example, vector biology, is very welcome. This award is for individual investigators and does not support collaborative teams. Award recipients are required to devote at least 75 percent of their overall time to research-related activities.

    Amount: $500,000 over 5 years

    Pre-proposal Due Date: September 1, 2017

    Full proposal submissions accepted by invitation only.

    RFP

  • Extracellular Vesicles and Substance Use Disorders (R01, R21)

    NIDA seeks applications for the following awards:

    - Extracellular Vesicles and Substance Use Disorders (R01) RFP

    - Extracellular Vesicles and Substance Use Disorders (R21) RFP

    The purpose of these FOAs is to encourage research projects that investigate the interplay between extracellular vesicles (EVs) and substance use disorders (SUDs). In particular, NIDA is interested in the potential utility of EVs with respect to understanding neuroplastic mechanisms relevant to SUDs or as biomarkers or therapeutics.

    Deadlines (for both awards): November 3, 2017, March 3, 2018, November 3, 2018, March 3, 2019, November 3, 2019, March 3, 2020

    For more information about these awards, please click here.

  • Junior Investigator Research Award - Epilepsy

    The American Epilepsy Society Junior Investigator Research Awards support basic, translational, or clinical epilepsy research by recently independent investigators and are intended to facilitate successful competition for subsequent longer term support from the NIH or other sources. Proposals are welcome across the spectrum of basic, translational, and clinical epilepsy research, including studies of disease mechanisms or treatments, epidemiologic or behavioral studies, the development of new technologies, and health services and outcomes research. Applicants must hold an M.D., Ph.D., PharmaD, RN, or equivalent degree and have an academic appointment at the level of Assistant Professor or equivalent at a university, medical school, research institution, or medical center.

    Amount: $50,000

    Pre-Application Deadline: October 5, 2017

    Application Deadline: January 21, 2018

    RFP

  • HIV-associated neuropathic pain and opioid interaction (R01)

    The purpose of this RFA is to promote research investigating the underlying mechanisms by which opioids including prescription drugs exacerbate HIV-associated neuropathic pain. Results from these studies may help obtain information for developing safe and effective treatments of neuropathic pain for HIV-infected patients exposed to opioids. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for support. 

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project. The direct cost of an application must be less than $500,000.

    Pre-Application Deadline: 30 days prior to the application deadline

    Application Deadline: December 18, 2017

    RFP

  • NIBIB Exploratory/Developmental Research Grant Program (R21)

    This FOA will support exploratory/developmental research programs of interest to the NIBIB. These studies are expected to lead to breakthroughs in development of innovative techniques, agents, methodologies, models, or their applications. These studies may involve considerable risk that should be balanced by the potential high impact on human-health and related research. Applicants are expected to propose novel biomedical research approaches for which there is no preliminary data to demonstrate the feasibility of the proposed project. A project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for support.

    Amount: Application budgets may not exceed $275,000 direct costs over a maximum two-year funding period. No more than $200,000 in direct costs may be requested in any single year.

    Deadline: October 16, 2017

    RFP

  • Neilsen Foundation Psychosocial Research Grants - Pilot Grants

    The Craig H. Neilsen Foundation seeks applications for Psychosocial Research Grants. The Psychosocial Research (PSR) portfolio supports research that addresses the interrelation of behavior, social, psychological and other quality of life factors that will benefit people living with spinal cord injury. The goal of the portfolio is to develop sound data to inform and disseminate best practices that produce better outcomes, including quality of life, for people living with spinal cord injury and their loved ones. Areas of interest include: aging, caregiving, employment, health behaviors and fitness, independent living, self-management and technology access.

    Applicants must have a doctoral degree or an equivalent terminal professional degree (e.g., PhD, MD, DVM). Non-fellowship applicants must demonstrate appropriate experience to serve as an independent Principal Investigator (PI). The Neilsen Foundation encourages submissions from eligible PIs who represent a wide range of disciplines; however, it is required that relevant SCI expertise is represented on the proposed research project team. 

    Amount: $200,000

    Pre-Application Deadline: March 30, 2018

    Application Deadline: July 2, 2018

    RFP

  • NINDS Landis Award for Outstanding Mentorship

    Excellent mentorship and training are critical to the development of exceptional future scientists. To recognize the contributions and importance of outstanding mentors, the National Institute of Neurological Disorders and Stroke (NINDS) has established the NINDS Landis Award for Outstanding Mentorship by a NINDS Investigator. This new annual award is named in honor of former NINDS Director Dr. Story Landis. An extraordinary individual mentor, Dr. Landis generously provided her time and energy to support countless scientific investigators as they navigated the professional landscape of biomedical research. Each year, NINDS will select up to five (5) Landis Awardees from among faculty members who have shown dedication to superior mentorship and training in neuroscience research. Current or former trainees can nominate faculty members who served as their mentors, and nominees will then be invited to submit additional supporting information. 

    Amount: Awardees will receive $100,000 (direct costs), in the form of a supplement to an existing NINDS grant

    Deadline: December 15, 2017

    RFP

  • Frontotemporal Degeneration Clinical Research

    The Association for Frontotemporal Degeneration (AFTD) seeks applications for Clinical Research Pilot Grants. These grants provide seed funding for innovative research projects in the preliminary stages of development with the potential to address the unmet medical needs of frontotemporal degeneration (FTD). The FTD disorders include: behavioral variant FTD, primary progressive aphasia, progressive supranuclear palsy, corticobasal syndrome, and FTD-ALS/MND. Applications are welcome from investigators at not-for-profit institutions as well as for-profit organizations. Pilot Grant funded projects are intended to generate data to support follow-on grant applications to the NIH or other public or private agencies. New or early-stage investigators/faculty in the process of establishing an independent research program are invited to apply. 

    Amount: $60,000

    Deadline: September 8, 2017

    RFP

  • Daland Fellowships in Clinical Investigation

    The American Philosophical Society awards a limited number of Daland Fellowships in Clinical Investigation for research in the several branches of clinical medicine, including internal medicine, neurology, pediatrics, psychiatry, and surgery. The committee emphasizes patient-oriented research. The fellowships are designed for qualified persons who have held an M.D. or M.D./Ph.D. degree for fewer than eight years. The fellowship is usually intended to be the first post-clinical-training fellowship, but each case will be decided on its merits. Preference is usually given to candidates who have not more than two years of postdoctoral training and research. Applicants, both U.S. citizens and foreign nationals, must expect to perform their research at an institution in the United States, under the supervision of a scientific advisor. Direct contact with patients is required.

    Stipends for the fellowship are $40,000 for the first year and $40,000 for the second year. The term of the fellowship is one year, with renewal for one year if satisfactory progress is demonstrated. The Society provides no funds for institutional overhead. The Society expects that essentially 100% of the Fellow's time will be devoted to research. With the cognizance of the committee, teaching or clinical service of a limited amount is permitted.

    Amount: Up to $80,000 over two years

    Deadline: September 15, 2017

    RFP

  • Clinical Investigator Career Development Award (2018-2021)

    The Lymphoma Research Foundation (LRF) is dedicated to finding a cure for lymphoma through an aggressively funded research program and by supporting the next generation of lymphoma researchers. In addition, the foundation provides education for people with lymphoma, their loved ones and caregivers, including comprehensive disease guides and fact sheets, in-person conferences, and online resources.

    To advance this mission, the foundation is accepting applications for its 2018-21 LRF Clinical Investigator Career Development Award program, which is designed to support physician-investigators at the level of advanced fellow or junior faculty member who can contribute to the development of new lymphoma therapies and diagnostic tools. The goal of the program is to prepare physician-investigators to design and administer clinical research studies in lymphoma and assume primary responsibilities for clinical research, protocol writing, Institutional Review Board (IRB) submission, and publication. To be eligible, applicants must be an investigator with no more than five years of experience beyond completion of their fellowship or postdoctoral training (the five-year limit may be non-sequential in cases of pregnancy or illness).

    Amount: $225,000 over three years

    Deadline: September 6, 2017

    RFP

  • Hirshberg Foundation 2017 Seed Grant Program

    The Hirshberg Foundation for Pancreatic Cancer Research Seed Grant program has been extremely successful in providing research support to basic and clinical scientists and investigators in the United States and overseas. To date the foundation has provided over $6 million for this program. The goals of the program are to: provide start-up funding for basic scientists and clinicians who intend to test innovative ideas for improving diagnosis and to develop new treatment modalities for pancreatic cancer; obtain preliminary data required for additional funding from other agencies for pancreatic cancer research; impact on the understanding of pancreatic cancer cell biology, biochemistry, physiology, morphology and response to therapy; and establish collaborations within the field for mutual projects that can be considered for further funding. 

    Eligibility and expectations: Doctor of Medicine (M.D.) or Doctor of Philosophy (Ph.D.) degree. Academic institutions of the U.S. and their investigators with the intent of developing a strong curriculum in pancreatic cancer research. All levels of academic faculty (assistant, associate and full professors). Research scientists and research associates with recommendations from their academic faculty supervisor(s). Postdoctoral fellows and young investigators after two years of completed training in pancreatic cancer research in any academic or private institution of the U.S. The Foundation expects that seed grant awards will generate quality abstracts, papers, presentations, as well as new proposals. The Foundation seeks and supports investigators whose primary intent is to build a strong curriculum in pancreatic cancer research.

    Amount: Up to $40,000 per year

    Deadline: August 15, 2017

    RFP

  • Alzheimer's Disease Research Program Awards

    The Bright Focus Foundation (BFF) seeks applications for the following Alzheimer's Disease Research Program Awards:

    - Postdoctoral Fellowship Awards

    Postdoctoral fellowship awards are intended for young researchers in their final stages of mentored training. These awards fund projects in an established laboratory that will serve as the basis for the applicant's own independent research career. Postdoctoral Fellowships are available to junior and senior postdoctoral fellows. Applicants with pending appointments are eligible to apply, but the appointment must be finalized by the start of the award. The proposal should be initiated by the postdoctoral fellow and not the supervisor.

    Amount: $150,000

    - Standard Awards

    The standard award provides significant funding for researchers who have already generated some amount of preliminary data, but are often required to demonstrate additional, significant progress before they can apply to governmental or industrial funding agencies. The Principal Investigator (PI) position on BrightFocus Standard Awards are open to tenure- and non-tenure track investigators of any career stage who are appropriately trained to lead an independent research study, and are permitted by their organizations to manage grants and supervise key personnel.

    Amount: $300,000

    Deadline (for both award types): October 18, 2017

    RFP

  • Pediatric Epilepsy Research Foundation (PERF) Grant for Infrastructure/Registry Research

    The Pediatric Epilepsy Research Foundation (PERF) seeks applications for the "PERF Grant for Infrastructure/Registry Research," a competitive grant in child neurology is directed at developing new infrastructure (i.e., registries and networks) or an existing infrastructure to advance the science of the research project. PERF will consider projects in all areas of child neurology, though research projects that promote advances in pediatric epliepsy and provide opportunities for training and/or mentoring young investigators are of particular interest. To be eligible for this grant, the applicant should be a child neurologist at any stage in his or her career and must be a legal resident of the United States or Canada.

    Amount: $200,000

    Pre-proposal Deadline: November 30, 2017

    Application Deadline: March 12, 2018

    RFP

  • Klingenstein-Simons Fellowship Awards in the Neurosciences

    The Klingenstein-Simons Fellowship Awards in Neuroscience support, in the early stages of their careers, young investigators engaged in basic or clinical research that may lead to a better understanding of neurological and psychiatric disorders. The Klingenstein Fund and the Simons Foundation recognize that to accomplish this goal it is necessary to encourage a variety of new approaches.

    To qualify for an award investigators must hold the Ph.D. and/or M.D. degrees, and have completed all research training, including post-doctoral training. The candidate must be an independent investigator, within 4 years of receiving his/her first tenure track appointment at a university or medical institution. U.S. citizenship is not a requirement, but it is expected that candidates will be permanent residents of the U.S. and that their research will be carried out in U.S. institutions.

    Amount: $225,000

    Deadline: February 15, 2018

    RFP

  • Michael J. Fox Foundation (MJFF) Awards

    The Michael J. Fox Foundation for Parkinson's Research (MJFF) seeks applications for the following awards:

    - Mitochondrial Biomarkers for Parkinson's Disease RFP

    - The Edmond J. Safra Fellowship in Movement Disorders RFP

    - Therapeutic Pipeline Program RFP

    - Target Advancement Program RFP

    For more information about these awards, please click here.

  • Chemical Probes for Novel Brain Targets (R01, R21)

    These FOAs intend to support investigators who have interest and capability to join efforts for the discovery of in vivo (R01) or cell-based (R21) chemical probes for novel brain targets. It is expected that applicants will have in hand the starting compounds (“validated hits”) for chemical optimization and bioassays for testing new analog compounds. Through these FOAs, NIH wishes to stimulate research in 1) discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of NIMH, NEI, NIAAA, NIDA, NIA and/or NIDCD and 2) discovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms. Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.

    - Discovery of in vivo Chemical Probes for Novel Brain Targets (R01) RFP

    - Discovery of Cell-based Chemical Probes for Novel Brain Targets (R21) RFP

    For more information about these awards, please click here.

  • Gates Foundation Novel Artemisinin Manufacturing Technologies Program

    The Bill & Melinda Gates Foundation has issued a Request of Proposals for its Novel Artemisinin Manufacturing Technologies program. The goal of the project is to develop novel approaches through the proof-of-concept stage for the manufacture of artemisinin and/or its precursors as a starting material or intermediate for the preparation of artemisinin-based active pharmaceutical ingredients. These approaches should demonstrate the potential — with a high probability of success — to meet aggressive cost targets when introduced at commercial scale.

    The focus of the RFP is on early research and lab-scale proof-of-concept testing of novel technologies. Awards will be made in three target areas, including artemisinin precursor (i.e., AA) production, chemical conversion of AA to artemisinin, and the direct production of artemisinin. The total value of all awards combined is estimated at $4.5 million, with individual awards not to exceed $1 million each for programs of up to twelve months. As the foundation recognizes that many interested parties may not have all the requisite capabilities in-house, proposers are highly encouraged to collaborate with partners, if needed. It is anticipated (but not guaranteed) that successful awardees will be requested to submit a proposal for additional development work, scale-up to pilot scale, generation of the necessary materials (e.g., cell banks), and technology transfer packages to enable manufacturing at multiple existing manufacturing facilities. To be eligible, applicants must be open to collaboration; be committed to providing global access to the technologies developed for the ultimate manufacturing of artemisinin; and be in good financial health. There are two deadlines to accommodate 1) potential rapid responses and awards for responders that can meet the tighter timelines (8/4/17); and 2) to allow for more time where it is required for partnering and/or the crafting of responses (9/29/17).

    Amount: Up to $1,000,000

    Deadline(s):

    - Concept Memorandum submission due August 4, 2017

    - Concept Memorandum Template due September 29, 2017

    RFP

  • ACA/MRA Cancer Related irAEs Research Program

    In recognition of the immense potential of checkpoint inhibition in combating multiple cancers and the reality that immune-related adverse events (irAEs) pose a challenge that, if addressed, could lead to better overall outcomes for patients and broader use, the American Cancer Society (ACS) and the Melanoma Research Alliance (MRA) have partnered to support research leading to the reduction of irAEs and the improvement of overall outcomes for cancer patients treated with checkpoint immunotherapy. To that end, the two organizations have issued a Request for Applications for projects that test feasibility and generate preliminary data. MRA and ACS have each committed $1 million for the awards. The combined $2 million will be used to fund Multidisciplinary Team Awards and Pilot Awards.

    1) Multidisciplinary Team Awards: At least one grant of up to $1 million will be awarded in this category to foster interdisciplinary collaborative research and promote transformational advances with the potential for rapid clinical benefit. Letters of Intent must be received no later than August. Upon review, selected applicants will be invited to submit a full application by October 31, 2017.

    2) Pilot Awards: Up to five grants of up to $200,000 each will be awarded over two years to help seed the ground in this relatively young area of checkpoint irAE research. Applications must be received no later than October 16, 2017.

    Both categories are designed to support research on the prevention, early detection, reduction, and/or management of life-altering and/or outcome-limiting side-effects of checkpoint inhibitor therapy. Projects should focus on research leading to mitigation of irAEs while preserving or enhancing checkpoint blockade effectiveness. Research topics of interest include but are not limited to the biological basis and mechanism of irAEs; prevention of irAEs; detection and biomarkers; measurement of symptom clusters; and clinical translation of research.

    Amount: $200,000 for Pilot Awards: $1,000,000 for Multidisciplinary Team Award

    Deadline: October 16, 2017

    RFP

  • ASCRS Career Development Grants

    The Research Foundation of the American Society of Colon and Rectal Surgeons (ASCRS) is accepting applications for its Career Development Grant program. The annual program provides young surgeons with the support necessary for the initiation and development of an academic career in colorectal surgery, with a focus on career development and mentorship of the individual rather than solely on the research proposal. Grants of up to $150,000 over two years will be awarded to academic investigators who demonstrate significant creativity in research relevant to the pathophysiology or management of diseases of the small bowel, colon, rectum, or anus.

    To be eligible, applicants must be within five years of their first full-time faculty appointment in a public or private nonprofit medical institution in the United States or Canada. Applicants also must be a citizen of the U.S. or Canada who has completed an approved colorectal surgery training program; if a foreign national, he or she must have a valid working visa at the time of application. All applicants must be an ASCRS member in good standing.

    Amount: Up to $150,000

    Deadline: October 1, 2017

    RFP

  • Clinical Research Sites for the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT sites) (U24)

    The purpose of this FOA, issued by NINDS, is to invite currently awarded NeuroNEXT sites and potential new sites to participate as a Clinical Site in the Network for Excellence in Neuroscience Clinical Trials (NeuroNEXT). This clinical research network develops and conducts multiple, scientifically sound, possibly biomarker-informed exploratory clinical trials evaluating the most promising therapies for neurological disorders, whether from academic, foundation or industry discoveries. Examples include Phase 2 clinical trials and clinical research studies aimed at validating biomarkers and clinical outcomes in preparation for clinical trials. The network provides a robust, standardized, and accessible infrastructure to facilitate rapid development and implementation of protocols in neurological disorders affecting adult and/or pediatric populations. While the network is not specific to one disease, it has the capacity to coordinate a cadre of specialist investigators to implement studies efficiently in response to disease-specific opportunities. This FOA solicits applications for Clinical Sites. Separate FOAs solicit applications for the Clinical Coordinating Center and the Data Coordinating Center. The PD/PI must be a clinical trials expert with neurology trial expertise and a track record in successfully implementing clinical trials. 

    Amount: The maximum allowable direct cost per year for a NIH NeuroNEXT site will be $200,000

    Letter of Intent Deadline: New Date - August 26, 2017

    Application Deadline: New Date - September 26, 2017

    RFP

  • DoD Epilepsy Research Program Awards

    The U.S. Department of Defense is seeking applications for the following FY17 Epilepsy Research Program Awards:

    - Epilepsy Risk Factors Award RFP

    - Idea Development Award RFP

    Letter of Intent Deadline (for both awards): September 6, 2017

    Application Deadline (for both awards): September 20, 2017

    For more information regarding these awards, please click here.

  • Central Neural Mechanisms of Age-Related Hearing Loss (R01)

    The purpose of this FOA, issued by NIA and NIDCD, is to encourage basic or clinical research applications that investigate central neural mechanisms of age-related hearing loss in older adults and/or in relevant animal models. This FOA is driven by the need to address a major gap in our understanding of the central pathways and neural networks that are involved in hearing loss and how these may be altered in the context of the aging brain, as well as how natural aging influences central auditory plasticity.

    Amount: Application budgets are limited to $500,000 in direct costs per year

    Letter of Intent Deadline: October 8, 2017

    Application Deadline: November 8, 2017

    RFP

  • First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Devices for Psychiatric Disorders (U01)

    The purpose of this FOA, issued by NIMH, is to encourage cooperative agreement applications to support early stage clinical trials of novel mechanism of action, investigational drugs or drug candidates for the treatment of psychiatric disorders in areas of unmet medical need. The FOA will support milestone-driven early stage trials in pediatric and adult populations. First in human (FIH) and Phase Ib studies of novel Agents must assess target engagement (brain exposure), pharmacological effects, safety, and tolerability to assess feasibility for Phase II/proof of concept (PoC) studies in psychiatric disorders. PoC studies must evaluate the drug’s impact on clinically relevant physiological systems (functional measures) and clinical indicators of effect. The FOA also supports FIH and early feasibility studies (EFS) of novel devices to evaluate target engagement, safety, tolerability, and efficacy. The overall objective is to facilitate rapid collection of data to "de-risk" novel mechanism of action investigational drugs, novel drugs for use in pediatric populations with psychiatric disorders, and devices or combination treatments in order to attract private funding for further clinical development as FDA-approved treatments. A key aspect of this FOA is the formation of collaborative partnerships between the biomedical researchers and biotechnology or industry researchers to facilitate psychiatric drug or device development.

    For pediatric drug trials, the application must include the joint participation of a pediatric pharmacologist and pediatric psychiatrist, as multiple PIs. Additionally, it is required that Contract Research Organizations (CROs) or CTSAs, with expertise in first in pediatric PK/PD bridging studies, will conduct the trial(s). Additionally, for all other trials that fit the goals of this FOA, it is required that CROs or CTSAs with expertise in the age range and intervention type, conduct the trials.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Letter of Intent Deadline: 30 days prior to the application deadline

    Application Deadline: October 5, 2017

    RFP

  • Alzheimer’s Drug Discovery Biomarker Studies Program

    Clinical trials for Alzheimer's disease and related dementias have been hindered, in part, by the limited number of biomarkers available to (1) accurately diagnose these diseases, (2) enrich and stratify patient cohorts, (3) demonstrate target engagement for novel therapeutics, and (4) reliably monitor disease progression and response to treatment. While currently available biomarkers have helped to accelerate clinical trials, most are either expensive, invasive, or both, and provide information on a small number of disease targets. Thus, additional biomarkers are needed to provide a more complete picture of the disease. To that end, the Alzheimer's Drug Discovery Foundation has issued a Request for Proposals to support the development and validation of biomarkers that will enhance the design and performance of clinical trials for Alzheimer's disease, related dementias, and cognitive aging.

    Grants of up to $300,000 over two years will be awarded in support of projects related to the development of biomarkers previously identified in samples from well-characterized human subjects. Validated methods should be used in quantifying and qualifying biomarkers, and the organization will give lower priority to the development of novel technologies. Priority biomarker areas include companion biomarkers, neuroimaging, CSF and blood-based biomarkers, and functional activity measures. Eligible applicants include academic investigators seeking to create and support innovative biomarker programs in academic medical centers and universities, and biotechnology companies with programs dedicated to Alzheimer's disease biomarker development. Funding is provided through mission-related investments that require return on investment based on scientific and/or business milestones.

    Amount: Up to $300,000/year for up to 2 years

    Letter of Intent Deadline: July 31, 2017

    RFP

  • CIGNA Foundation Grants in Community Health Navigation

    The Cigna Foundation is deeply committed to providing opportunities for individuals everywhere to achieve the best possible health. The Foundation pursues this goal through providing World of Difference Grants that focus on Health Equity, helping people overcome barriers to their health and well-being related to factors such as ethnicity, race, gender, age, geography, or economics.

    World of Difference Grants emphasize partnership: sharing the knowledge and expertise of Cigna's professionals with dedicated non-profit partners. Individuals can’t achieve their best possible health if they don’t understand the health challenges they face. They can’t access community health resources if they don’t know they exist. The solution to both dilemmas is Community Health Navigation—projects and programs aimed at connecting individuals and better health through the efforts of trusted neighbors and organizations. A well-designed Community Health Navigation program can be a powerful tool in bringing improved Health Equity to underserved populations. Community Health Navigation can take many forms. Often it starts with faith-based organizations. In other cases, neighborhood clinics or emergency medical workers may play a role.

    Amount: Up to $200,000

    Deadline: Applications accepted on a rolling basis

    RFP

  • BRAIN Initiative: New Concepts and Early - Stage Research for Large - Scale Recording and Modulation in the Nervous System (R21)

    This FOA seeks applications for unique and innovative technologies that are in an even earlier stage of development than that sought in other FOAs, including new and untested ideas that are in the initial stages of conceptualization. In addition to experimental approaches, the support provided under this FOA might enable calculations, simulations, computational models, or other mathematical techniques for demonstrating that the signal sources and/or measurement technologies are theoretically capable of meeting the demands of large-scale recording or manipulation of circuit activity in humans or in animal models. The support might also be used for building and testing phantoms, prototypes, in-vitro or other bench-top models in order to validate underlying theoretical assumptions in preparation for future FOAs aimed at testing in animal models. Invasive or non-invasive approaches are sought that will ultimately enable or reduce the current barriers to large-scale recording or manipulation of neural activity, and that would ultimately be compatible with experiments in humans or behaving animals. Applications are encouraged from any qualified individuals, including physicists, engineers, theoreticians, and scientists, especially those not typically involved with neuroscience research. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for support.

    Amount: The combined direct cost budget for the two-year project period may not exceed $300,000. No more than $200,000 may be requested in any single year

    Deadline: October 26, 2017

    RFP

  • DoD Peer Reviewed Alzheimer's Research Program Awards

    The U.S. Department of Defense is seeking applications for the following FY17 Peer Reviewed Alzheimer's Research Program (PRARP) Awards:

    - Convergence Science Research Award RFP

    - New Investigator Research Award RFP

    - Research Partnership Award RFP

    - Quality of Life Research Award RFP

    Letter of Intent Deadline (for all awards): September 6, 2017

    Application Deadline (for all awards): September 20, 2017

    For more information regarding these awards, please click here.

  • Genetech Age-related Macular Degeration Research Fellowships

    The ARVO Foundation for Eye Research, the philanthropic arm of the Association of Research in Vision and Ophthalmology, was established in 2001 to ensure stable support for innovative and novel vision research, particularly work with translational impact that fosters collaboration between clinicians and basic scientists.

    The foundation is inviting applications for two Genentech Age-Related Macular Degeneration Research Fellowships in support of research related to age-related macular degeneration. A single grant of $40,000 grant will be awarded to a basic researcher working to advance the understanding of AMD, while a second grant of $40,000 will be awarded to an AMD researcher focused on therapeutics. To be eligible, applicants must be a newly established investigator age 45 or younger at the time of application. While ARVO membership is not necessary, applicants must currently be working in a nonprofit or academic research center.

    Amount: $40,000

    Deadline: September 1, 2017

    RFP

  • Clinical Research Training Fellowship in Parkinson's Disease - Funded by Lundbeck

    The American Academy of Neurology (AAN) is pleased to support clinical research training in the neurosciences. This award aims to recognize the importance of good clinical research and to encourage young investigators in clinical studies. The AAN Research Program demonstrates the AAN Board of Directors dedication to promoting neurology and neuroscience research and training. Recipient must be an AAN member interested in an academic career in neurological research who has completed residency or a PhD no more than 5 years prior to the beginning of this award.

    Amount: $55,000 per year for two years, plus a $10,000 per year stipend to support education and research-related costs for a total of $130,000

    Deadline: October 1, 2017

    RFP

  • Targeted Research Initiative for Cannabinoids and Epilepsy (TRICE)

    The Epilepsy Foundation supports translational, clinical and behavioral research leading to advances into the diagnosis and care of persons with seizures and epilepsy. The Epilepsy Foundation is pleased to continue its Targeted Research Initiative program on Cannabinoids, in recognition of the critical need for research on cannabidiol and other cannabinoids and their potential for therapeutic development for treatment of epilepsy. Investigators must hold a relevant advanced degree (MD, PhD, MS, PharmD), and have completed all research training appropriate to the project proposed. This call for proposals is open to investigators at academic/university settings and others in the public and private sectors.

    Amount: $50,000

    Deadline: September 25, 2017

    RFP

  • Toyota Foundation Research Grant Program

    The goal of the Toyota Foundation is to contribute toward the realization of a more people-oriented society and a resulting increase in human happiness. The Foundation provides research and operations grants to identify a diverse array of social issues, with a focus on areas of human and natural environment, social welfare, and education and culture. These grants support projects based on foresight, a participatory orientation, and an international perspective.

    The objective of the Toyota Foundation “Exploring New Values for Society” Research Grant Program is to encourage ambitious projects that seek new values for society by fundamentally exploring basic ways of thinking and methodologies on what approach we should take to address difficult issues to be faced in the future. 

    The program has two grant categories for joint research projects and individual research projects, both of which places no restrictions on the areas of research or the methods employed. For both categories, funded projects will be founded on creative concepts that reflect a youthful perspective and draw closer to new values for society, disseminating their findings effectively in many directions and springing up a range of lively discussions.

    For more information, please click here.

    RFP

  • NSF Cognitive Neuroscience Program Award

    The Cognitive Neuroscience Program (CogNeuro) seeks highly innovative proposals aimed at advancing a rigorous understanding of the neural mechanisms of human cognition. Central research topics for consideration by the program include attention, learning, memory, decision-making, language, social cognition, and emotions. Proposals with animal models are appropriate only if they include a comparative element with human subjects.

    Amount: The average award size is ~$175,000 per year (including both direct and indirect costs) and the average duration is 3 years

    Deadline(s): August 14, 2017; February 12, 2018

    RFP

  • Alpha-Synuclein Imaging Prize - Michael J. Fox Foundation

    The Michael J. Fox Foundation (MJFF) seeks contestants for its Alpha-Synuclein Imaging Prize. The ability to image alpha-synuclein deposition in the brain would be a game-changing achievement for the Parkinson's disease (PD) field. The accumulation of aggregated alpha-synuclein is a pathological hallmark of PD and a priority target for drug development given its hypothesized contribution to neurodegeneration. In vivo imaging of alpha-synuclein pathology could be useful as a biomarker of the presence of disease and disease progression and as a pharmacodynamic tool for drug development. With this prize, the Foundation seeks to attract research teams and accelerate momentum to speed the development of such a tracer. Anyone is eligible for the prize who agrees to all contest rules. Contestants may be, though need not be, MJFF funded and can be from either academia or industry.

    Amount: $2,000,000

    Deadline: There is no deadline for submissions. The award will be issued to the first contestant who submits compelling evidence of a viable selective tracer and agrees to its widespread use. If no award is given by mid-2018, the MJFF will evaluate the state of the field and utility of such a prize.

    RFP

  • Mobile Monitoring of Cognitive Change (U2C)

    This FOA, issued by the National Institute on Aging, invites applications to design and implement research infrastructure that will enable the monitoring of cognitive abilities and age, state, context, or health condition-related changes in cognitive abilities on mobile devices. This effort will include the development (or support for development) of apps on the Android and iOS platforms, the validation of tests and items to be used on the two leading smartphone platforms in age groups ranging from 20 to 85, and the norming of successfully validated measures to nationally representative U.S. population samples that will also receive gold standard measures, including the NIH Toolbox® for Assessment of Behavioral and Neurological Function. A goal of this project is to also support data collection efforts from participants enrolled in projects awarded through this FOA as well as other NIH-funded studies though FY2022, and enable the widespread sharing of both the collected data and the test instruments. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Letter of Intent Deadline: October 2, 2017

    Application Deadline: November 2, 2017

    RFP

  • Cognitive Decline and Cognitive Reserve Funding from Alzheimer's Drug Discovery Foundation

    Cognitive decline through aging and health conditions has been linked to an increased risk of dementia. The Alzheimer's Drug Discovery Foundataion (ADDF) will consider funding drug discovery programs to prevent and treat these conditions, including cognitive aging, postoperative delirium and postoperative cognitive decline, mild and/or repetitive traumatic brain injury, and chemotherapy-induced decline. Methods may include clinical trials or epidemiology. ADDF encourages proposals from academic investigators seeking to create and support innovative programs in academic medical centers and universities.

    Amount: Epidemiological Analyses- $50,000-$100,000; Clinical Trials- up to $3 million

    Letter of Intent Deadline(s): July 31, 2017; November 17, 2017

    Application submissions accepted by invitation only.

    RFP

  • 2018 Young Investigator Program - Beckman Foundation

    The Arnold and Mabel Beckman Foundation is accepting Letters of Intent for its 2018 Beckman Young Investigator grant program. The annual program is intended to provide research support to the most promising young faculty members in the early stages of an academic career in the chemical or life sciences and to foster the invention of methods, instruments, and materials with the potential to open up new avenues of research in science. Projects proposed for this program should be truly innovative, high-risk, and show promise for contributing to significant advances in chemistry and the life sciences. They should also represent a departure from current research directions rather than an extension or expansion of existing programs. Proposed research that cuts across traditional boundaries of scientific disciplines is encouraged. Proposals that open new avenues of research in chemistry and life sciences by fostering the invention of methods, instruments and materials will be given additional consideration.

    Eligibility: The BYI program is open to those within the first three years of a tenure-track position, or an equivalent independent research appointment, at a United States academic or non-profit institution that conducts research in chemical and life sciences. Tenure Track Start Date must be after: 8/14/2014 Candidates must be citizens or permanent residents of the United States at the time of application. Persons who have applied for permanent residency but have not received their government documentation by the time of application are not eligible. No individual may apply for a Beckman Young Investigator award more than two times. Investigators can have no more than $225,000 in direct, annualized external funding grants during any BYI Program Year (Aug-July) at time of application. Start-up funds, department-wide instrumentation grants, and "Transition" grants (such as NIH K99/R00) are not counted toward this total. Institutions are not limited in the number of applicants who apply at the Letter of Intent stage. Institutions with a currently funded BYI are eligible for award consideration.

    Amount: Grants typically range around $600,000 over the term of the project. Projects are normally funded for a period of four years

    Deadline: August 14, 2017

    RFP

  • Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33)

    The purpose of this FOA is to support the early stage testing of pharmacologic interventions with novel mechanisms of action, or device-based interventions, for the treatment of symptoms or domains of altered functions in individuals with mental illness (e.g. schizophrenia, depression, autism, obsessive compulsive disorder, anxiety, bipolar disorder, etc.). Early intervention studies are also encouraged where symptoms of a disorder have been identified in subjects (a prodromal phase), prior to full diagnostic criteria being met. Ultimately, this FOA is intended to support early stage testing of pharmacologic or device-based interventions using a protocol design where the presumed mechanism of action of the intervention is adequately tested, to provide meaningful information where target modulation yields a dose-dependent neurophysiological/clinical/behavioral effect. The R61/R33 FOAs are intended to support biphasic high risk applications. Applicants looking for a single phased award that does not need the developmental (R61) phase should apply to companion RFA-MH-17-602. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Letter of Intent Deadline: 30 days prior to the application deadline

    Application Deadline(s): October 17, 2017; February 14, 2018; June 15, 2018; October 15, 2018

    RFP

  • Bioengineering Research Grants (BRG) (R01)

    The purpose of this FOA is to encourage collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical or translational science. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply for support.

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    Deadline(s): 10/5/2017, 2/5/2018, 6/5/2018, 10/5/2018, 2/5/2019

    RFP

  • NEI Center Core Grant for Vision Research (P30)

    The National Eye Institute (NEI) Center Core Grant combines three or more Resource and/or Service Cores for a group of R01 investigators to enhance their research, consolidate resources, avoid duplication of efforts, and/or contribute to cost effectiveness by providing a service with lower costs or higher quality than could be attempted for independent projects by several individual Program Directors/Principal Investigators (PD(s)/PI(s)). Shared resources and facilities that are accessible to a group of independently funded investigators lead to greater productivity for the separate projects and can provide instrumentation and facilities that are too costly to be maintained by an individual investigator. The design and purpose of each Center Core may vary in how it serves its users. This program is designed to enhance an institution's environment and capability to conduct vision research and to facilitate collaborative studies of the visual system and its disorders. Only one application per institution is allowed.

    Amount: The NEI will provide direct costs of up to $2,000,000 over a five-year period in support of a Core Grant to institutions having 8 to 19 eligible grants. Institutions having 20 or more eligible grants may receive direct costs of up to $2,500,000 over a five-year period

    Deadline(s): September 28, 2017; September 28, 2018, September 18, 2019

    RFP

  • NARSAD Distinguished Investigator Grant

    The National Alliance for Research on Schizophrenia and Depression (NARSAD) Distinguished Investigator Grants, awarded through the Brain & Behavior Research Foundation, provide support for experienced investigators (full professor or equivalent) conducting neurobiological and behavioral research. One-year grants of $100,000 each are provided for established scientists pursuing particularly innovative project ideas. Distinguished Investigator Grants fund talented, established scientists with a record of outstanding research accomplishments. These research projects might provide new approaches to understanding or treating severe mental illness. If successful, the grants could result in later funding from other sources. These grants are among the most competitive in mental health research and demonstrate the power of investigator-initiated research to bring out new and creative ideas. Applicants 1) Must be full professors (or equivalent) and maintain peer reviewed, competitively-funded scientific programs; 2) May not receive the award for a second time.

    Amount: $100,000

    Deadline: July 19, 2017

    RFP

  • SFARI Autism Research Awards

    The mission of the Simons Foundation Autism Research Initiative (SFARI) is to improve the understanding, diagnosis and treatment of autism spectrum disorders (ASD) by funding innovative research of the highest quality and relevance. SFARI is currently seeking applications for the following awards:

    - Bridge to Independence Award RFP

    - Explorer Award RFP

    For more information regarding these awards, please click here.

  • Sloan Research Fellows - Neuroscience

    The Alfred P. Sloan Foundation is a not-for-profit grantmaking institution that supports high quality, impartial scientific research; fosters a robust, diverse scientific workforce; strengthens public understanding and engagement with science; and promotes the health of the institutions of scientific endeavor. The Sloan Research Fellowships seek to stimulate fundamental research by early-career scientists and scholars of outstanding promise. Candidates must hold a tenure track (or equivalent) position at a college, university, or other degree-granting institution in the United States or Canada. Tenure track faculty positions at the candidate's institution must include a yearly teaching requirement. Candidates' most recent Ph.D. (or equivalent) must have been awarded on or after September 1, 2011.

    Amount: $65,000

    Deadline: September 15, 2017

    RFP

  • DoD FY17 Peer Reviewed Cancer Research Program Awards

    The goal of the U.S. Department of Defense Peer Reviewed Cancer Research Program (PRCRP) is to improve quality of life by decreasing the impact of cancer on active duty Service members, their families, and the American public. The PRCRP is charged by Congress with the mission to investigate cancer risks and knowledge gaps that may be relevant to active duty Service members, their families, other military beneficiaries, and the American public. To be considered for funding, applications must address at least one of the FY17 PRCRP Topic Areas and at least one of the FY17 PRCRP Military Relevance Focus Areas, which can be found here.

    The PRCRP is seeking pre-applications for the following awards:

    - Career Development Award RFP

    - Idea Award with Special Focus RFP

    - Translational Team Science Award RFP

    A Letter of Intent is required. Application submissions accepted by invitation only.

    For more information regarding these awards, please click here.

  • SU2C Dream Team Translational Cancer Research Grant

    Stand Up To Cancer (SU2C), in partnership with the American Association for Cancer Research, is inviting Letters of Intent for a new $10 million "Dream Team" grant. Unlike other "Dream Team" grant opportunities offered by SU2C in recent years, the SU2C Dream Team Translational Cancer Research Grant program is open to any type of translational cancer research. The program will support a single translational cancer research project that addresses a critical problem in patient care and has the potential to deliver near-term patient benefit through investigation by a multidisciplinary, multi-institutional, expert team of investigators.

    The proposed project may focus on a particular organ site, patient population (e.g., pediatrics), or innovative method of treatment. The project must be designed to accelerate the application of a new preventive, diagnostic, or therapeutic approach to the clinic that leads to patient involvement within two to three years from the beginning of the grant. In addition, through collaboration with leading healthcare research and innovation center OptumLabs, the team will have the opportunity to gain access to and conduct research using OptumLabs' proprietary database of de-identified medical claims and electronic health record clinical data, analytic tools, and research. To maximize creativity, innovation, and collaboration, the team of investigators must include laboratory and clinical researchers, senior and/or young investigators, and senior scientists who have not worked together in the past.

    Amount: $10,000,000

    Letter of Intent Deadline: September 5, 2017 - 11:00 am CST

    Proposals accepted by invitation only.

    RFP

  • Funderburg Research Award in Gastric Cancer

    The AGA Foundation, the philanthropic arm of the American Gastroenterological Association, is inviting applications for the Robert & Sally Funderburg Research Award in Gastric Cancer. The annual award is designed to support an established investigator whose research has the potential to enhance the fundamental understanding of gastric cancer pathobiology and ultimately lead to the prevention of or a cure for the disease. The recipient will be selected based on novelty, feasibility, and significance of his/her proposal.

    A single grant of up to $100,000 over two years will be awarded to an established investigator working on novel approaches in gastric cancer research, including the fields of gastric mucosal cell biology, regeneration and regulation of cell growth (not as it relates to peptic ulcer disease or repair), inflammation (including Helicobacter pylori) as precancerous lesions, genetics of gastric carcinoma, oncogenes in gastric epithelial malignancies, epidemiology of gastric cancer, etiology of gastric epithelial malignancies, or clinical research with respect to the diagnosis or treatment of gastric carcinoma. To be eligible, applicants must hold a full-time faculty position at an accredited institution in North America and be established as an independent investigator in the field of gastric biology. AGA membership is required at the time of application submission, and women and minority investigators are strongly encouraged to apply.

    Amount: Up to $100,000

    Deadline: August 4, 2017

    RFP

  • National Blood Foundation - Scientific Research Grants Program

    The National Blood Foundation (NBF), has announced the 2018 grant program for scientific research projects related to transfusion medicine and cellular therapies.

    NBF will award grants for investigator-initiated original research focused on any aspect of blood banking, transfusion medicine, cellular therapies, or patient blood management. Grants will support one- or two-year research projects with a maximum award of $75,000. Awards will not be made to increase the funding available for currently funded research projects. NBF grants are intended to provide seed funding that allows the principal investigator to enhance his/her preliminary data so that is useful in applying for bigger grants.

    An application fee of $160 must accompany the application unless the primary investigator is an AABB individual member. To be eligible, an applicant must be a doctor (MD or PhD), medical technologist, or transfusion medicine or cellular therapies professional. All applicants will be considered regardless of age, race, gender, national origin, or religion.

    Amount: $75,000

    Deadline: December 1, 2017 – 10:59 pm CST

    RFP

  • AAFPF Joint Grant Awards Program

    The American Academy of Family Physicians Foundation (AAFPF), through its Joint Grant Awards Program (JGAP), supports research of one- to two-year duration that poses questions of high relevance to family medicine. The maximum JGAP grant award is $50,000. Applications for smaller-scale studies with lower costs are also welcome. To be eligible, the principal investigator must be a family medicine researcher, either a clinician or PhD. In addition, the PI or a co-investigator must be a member of AAFP. Priority will be given to new researchers or those who mentor new investigators on the research team. Education and healthcare institutions or organizations that intend to use JGAP support exclusively for research projects directly involving and impacting family medicine are also eligible.

    Amount: $50,000

    Deadline: January 9, 2018

    RFP

  • NINDS Exploratory Clinical Trials for Small Business (R42)

    The purpose of this FOA is to provide a vehicle for Small Business Concerns (SBCs) submitting Small Business Technology Transfer (STTR) grant applications for investigator-initiated exploratory clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The projects must focus on products related to the mission and goals of the NINDS and may evaluate drugs, biologics, devices, or diagnostics, as well as surgical, behavioral or rehabilitation therapies. Only STTR Phase II and Fast-Track applications are supported under this program. STTR Phase I applications are only accepted as part of a Fast-track application. Only United States small business concerns (SBCs) are eligible to submit applications for this opportunity.

    Amount: According to statutory guidelines, total funding support (direct costs, indirect costs, fee) normally may not exceed $150,000 for Phase I awards and $1,000,000 for Phase II awards. With appropriate justification from the applicant, Congress will allow awards to exceed these amounts by up to 50% ($225,000 for Phase I and $1,500,000 for Phase II). However, NIH can apply for a waiver from SBA to issue an award exceeding these amounts under appropriate circumstances. Applications should rarely exceed $1,000,000 in total cost per year for a Phase I and $1,500,000 in total cost per year for a Phase II.

    Deadline(s): September 5, 2017; January 5, 2018; April 5, 2018

    RFP

  • Global Brain and Nervous System Disorders Research Across the Lifespan (R01, R21)

    This FOA encourages grant applications for the conduct of innovative, collaborative research projects between U.S. and low- and middle-income country (LMIC) scientists, on brain and other nervous system function and disorders throughout life, relevant to LMICs (including neurological, mental, behavioral, alcohol and substance use disorders and spanning the full range of science from basic to implementation research). Scientists in upper middle-income LMICs (UMICs) are also eligible to partner directly with scientists at other LMIC institutions with or without out a US partner. Income categories are defined by the World Bank. The collaborative research programs are expected to contribute to the long-term goals of building and strengthening sustainable research capacity in LMICs to address nervous system development, function and impairment throughout life and to lead to diagnostics, prevention, treatment and implementation strategies. The proposed work will also contribute to developing a base for research networking and evidence-based policy beyond the specific research project. 

    Research Project Grant (R01)

    Amount: Application budgets are not limited but need to reflect the actual needs of the proposed project

    RFP

    Exploratory/Developmental Research Grant Award (R21)

    Amount: Application budgets are limited to $125,000 per year in direct costs, but must reflect the actual needs of the proposed project

    RFP

    Letter of Intent Deadline (for both awards): 30 days prior to the application deadline

    Application Deadline(s) (for both awards): November 7, 2017; November 7, 2018; November 7, 2019

    For more information regarding eligibility, please click here.

  • DoD Parkinson’s Research Program Awards

    The U.S. Department of Defense is seeking applications for the following FY17 Parkinson's Research Program (PRP) Awards:

    - Investigator-Initiated Research Award RFP

    - Early Investigator Research Award RFP

    Letter of Intent Deadline (for both awards): August 17, 2017

    Application Deadline (for both awards): August 31, 2017

    For more information regarding these awards, please click here.